This is not an original thought.
In my opinion, the modern Ghostbusters sequels never quite “get there” in terms of being a success, because they’re focusing on the wrong things. They’re all about the nostalgia. The original was a huge success because the supernatural angle was just the dressing. Fun dressing, to be sure! But the heart of Ghostbusters (1984) was the schlubby, funny misfits led by a grifter, cynically exploiting a brand new area of science in order to make a buck…. and they just happen to end up saving the world. They had the tools and the talent: but if they weren’t making money doing it up to that point, we’d have all been screwed.
Even the name of the business is unglamorous: “Ghostbusters”. It’s “Dale’s Dead Bug” with the giant fake bug on the roof of the van, but with a ghost.
Hell, I’m not even sure you can make a true Ghostbusters “sequel” that doesn’t focus on the business aspect. The RLM guys had a great idea for a hypothetical Ghostbusters III (in the 90s). Venkman is basically CEO over a nationwide franchise of Ghostbusters locations across the country and they try to unionize, so he fires them all just as some new big threat emerges.
I can absolutely see that working, and in the spirit (hoho!) of the original.